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Rezolute's Rare Disease Drug Fails to Beat Placebo in Key Trial

Rezolute's ersodetug therapy for congenital hyperinsulinism failed Phase 3 trial, missing primary endpoints. Stock plunged 90% as the drug showed no significant advantage over placebo.

Rezolute's Rare Disease Drug Fails to Beat Placebo in Key Trial
Credit: Rezolute
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12/11/2025 · 9:00 AM
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FDA Approves First-Ever PROTAC Drug Veppanu for Advanced Breast Cancer with ESR1 Mutation
05/01/2026 · 12:56 PM

FDA Approves First-Ever PROTAC Drug Veppanu for Advanced Breast Cancer with ESR1 Mutation

FDA approved Pfizer/Arvinas Veppanu pill for advanced breast cancer with ESR1 mutation, helping hormone-resistant cases.

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The End of Spirit Airlines: Cheap Flights May Never Be the Same
Featured/ 05/01/2026 · 11:38 AM

The End of Spirit Airlines: Cheap Flights May Never Be the Same

Spirit Airlines may stop flying after failed $500M bailout; shares crash, flights uncertain, and fares may rise as competition drops.

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ExxonMobil Profit Falls to a 5-Year Low — but Adjusted Results Beat Expectations
05/01/2026 · 10:17 AM

ExxonMobil Profit Falls to a 5-Year Low — but Adjusted Results Beat Expectations

Exxon beat forecasts, but profit fell due to Middle East issues. Strong US output helped offset losses; cash returns to shareholders stayed high.

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